Finn Russell will not feature for Scotland in their opening Nations Championship match of the summer series against Argentina, while Jonny Gray makes his return after missing this year’s Six Nations.
Russell, 33, has not fully recovered from the calf injury that kept him out of the latter part of Bath’s domestic campaign while Gray, 32, last played in a Scotland jersey in the 2025 Six Nations.
Lock Scott Cummings, 29, and prop Pierre Schoeman, 32, will win their 50th caps at Estadio Mario Alberto Kempes in Cordoba on Saturday (20:10 BST).
Gregor Townsend’s side also play South Africa in Pretoria and Fiji at Murrayfield this month in the Nations Championship.
The XV that starts against the Pumas shows eight personnel changes to the team that finished the Six Nations with defeat to Ireland in Dublin in mid-March.
Full-back Kyle Rowe, centre Rory Hutchinson, wing Jamie Dobie, fly-half Tom Jordan, hooker George Turner, prop Elliot Millar-Mills and Cummings are the players joining Gray in coming in to the side.
Kyle Steyn moves from left to right to accommodate Dobie.
Prop Zander Fagerson and wing Darcy Graham, who started in Dublin, drop to the bench.
Scotland: Rowe, Steyn, Hutchinson, Tuipulotu (capt), Dobie, Jordan, White; Schoeman, Ashman, Millar-Mills, Gray, Cummings, M Fagerson, Darge, Dempsey
Replacements: Hiddleston, Sutherland, Z Fagerson, Samuel, Brown, Horne, Burke, Graham.